Prof. Dr.Diaa Najm Abdullah

Prof. Dr. Diaa Najm Abdullah Al-Sabha holds a doctorate from the College of Science at the University of Mosul in 1997 in the field of Analytical Chemistry. He obtained the rank of professor in 2010. He taught analytical chemistry at the College of Education for Pure Sciences, the College of Science, and the College of Pharmacy at the University of Mosul. He continues to teach the subject at the Faculty of Pharmacy at Al-Noor University College. He also taught various topics in analytical chemistry to graduate students at the universities of Mosul, Duhok, and Zakho. 12 master’s students and 13 doctoral students were supervised. He held several responsibilities at the University of Mosul, including Assistant Dean for Scientific Affairs and Graduate Studies, Head of the Chemistry Department in the College of Education for Pure Sciences, Chairman of the Scientific Promotions Committee in the College of Education for Pure Sciences, as well as a member of the Ministerial Committee in the Council for Improving the Quality of Education for the Colleges of the Educational Group. He served as head of the Chemists Syndicate in Nineveh Governorate. In addition, 80 research papers were published in international, Arab and local journals. • Participated in technical training for the operation and periodic maintenance of Shimadzu high-performance liquid chromatography (HPLC), GC and atomic absorption devices in Jordan. He participated in many foreign, Arab and local conferences.

E.mail Address

[email protected]

Department

Optics Techniques

Specialization

Analytical Chemistry

Number of published researches

79

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Most cited scientific research

Spectrophotometric assay of phenylephrine hydrocholride using 4-aminoantipyrine and copper (II)

Abstract :

A new spectrophotometric method is proposed for the determination of phenylephrine hydrochloride. The method is based on the coupling of 4-aminoantipyrine (4-AAP) with Phenylephrine Hydrochloride (PEH) to give a new ligand that reacts with copper (II) in the presence of sodium tetraborate buffer solution of pH9 at 50 C with an intensely red colored chelate having maximum absorption at 480 nm. The method has been used for the determination of 2.0–50.0 µg ml-1 of PEH with molar absorptivity of 5.357× 103 L. mol-1cm-1, average recovery of 101.28% and Relative Standard Deviation (RSD) of 1.25%. The results of the method were compared with those of the official method. The mechanism of the chemical reaction has been proposed. The proposed method was successfully applied for the determination of the PEH in pharmaceutical syrup formulations.

Use of charge transfer complex formation reaction in spectrophotometric microdetermination of some drugs

Abstract :

A spectrophotometric method is proposed for the determination of isoniazid, mesalazine, salbutamol and thymol drugs in their pure forms and in pharmaceutical preparations, based on the charge-transfer (CT) complex formation reaction with o-chloranil as π-acceptor. Linear calibration graphs were obtained in the concentration range 1-16 and 2-20 µg ml-1 for isoniazid at 360 and 520 nm respectively, 1.25-30 µg ml-1 at 571.5 nm for mesalazine, 1.25-50 µg ml-1 for salbutamol and 2.5-80 µg ml-1 at 410 nm for thymol at room temperature. The molar absorptivity values are in the range 3460 and 14360 l. mol-1. cm-1 and the lower limit of detection limits are in the rang 0.1432-1.3164 µg ml-1 for all the studied drugs. The stoichiometry of the drug-o-chloranil complexes was found to be 1: 1 except mesalazine which was found to be 1: 2. No interference was observed from common pharmaceutical excipients. Th Procedure is characterized by its simplicity with accuracy and precision. The proposed method was applied successfully for the determination of the drugs in their pharmaceutical formulations.

ٍSpectrophotometric Determination of Oxymetazoline Hydrochloride Based on the Oxidation Reactions

Abstract :

Simple, sensitive and reproducible spectrophotometric method was developed for determination of oxymetazoline hydrochloride in pure as well as in pharmaceutical drop formulations. The method is based on the reduction of ferric to ferrous ions followed by complexation with 1, 10-phenanthroline to produce an orange red chromogen that has maximum absorption at 510 nm and obeyed Beer’s linearity in the concentration range of 0.1-7 μg/ml, with molar absorptivity 5.74× 104 l. mol-1cm-1, accuracy (average recovery%) 100.53% and precision better than 1.6. The developed method was successfully applied to the determination of oxymetazoline hydrochloride in bulk and pharmaceutical formulations without any interference from common excipients.

Spectrophotometric determination of amikacin sulphate via charge transfer complex formation reaction using tetracyanoethylene and 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone …

Abstract :

A spectrophotometric method based on the complex formation reaction has been described for the determination of amikacin sulphate as n-donor with terecyanoethylene (TCNE) and 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone (DDQ) reagents as π-acceptors to give a colored complex species in aqueous solution which can absorb maximally at 330 and 340 nm, respectively. Beer's law is obeyed in the concentration ranges 0.4–6.8 and 0.8–20.0 µg/ml with high apparent molar absorptivities of 9.49× 104 and 1.91× 104 and limits of detections are 0.06 and 0.18 µg/ml, whereas the average recoveries are 96.54% and 99.47% when using TCNE and DDQ, respectively. The relative standard deviation is≤ 4. Application of the proposed method to commercial pharmaceutical injuctions is presented.